SPSS for Biologists: How to perform basic Fisher's or Chi-square test ?

SPSS for Biologists: How to perform basic Fisher's or Chi-square test?

SPSS (Statistical package for the social sciences) is the set of software programs that are combined together in a single package. This data can be mainly used for

                               

Interestingly, the 21st century is becoming testing times for all basic researchers who are not equipped with dealing the big data. These terms, data science or big data, look extremely challenging to researchers specially to biologists. 

Aim of Tutorials

The aim of making these tutorials is to help the biologists to improve  their skills to deal with large amount of biological data.The first and the most 

basic is how to use of Chi Square test/Exact Fisher Test.

CHI Square Test

                              

A Chi-square test is one way to show the relationship between two variables. Chi-Square statistics is the single number that tells you how much difference exists between expected count and the observed count.

The Chi Square statistic is commonly used for testing relationships between categorical variables. It is used to determine if there is a significant association between two variables. As in this tutorial,I have explained  in detail how to do it.

We have the dataset of different patients with details about the respective disease. For example their diagnostic Age, Stage of the disease, activeness and inactiveness  of the genes etc.

Considering each parameter as a variable, what we do is finding out the independency of each variable.  

• In biological terms we compare the gene activation/inactivation of each patient data with other clinical features like Metastasis,Tumour Stage and age etc.
• This test will give us the results of association between two or more variables, as we know P value less than 0.05 will be considered significant (showing the positive association).

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