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PHYLOGENETIC ANALYSIS:Difference between Distance based and Character based Methods

BASICS OF PHYLOGENETICS : Computational  Analysis of Distance and Character based methods

 Distance based Method :
Transform the sequence data into pairwise distances and then use the matrix during tree building ignoring the characters.
  1. The distance based phylogenetic methods measure the distance from the dissimilarity observe between pairs of sequences, computed on the basis of sequence alignment. 
  2. The main assumption of distance based methods is homologous and that tree branches can sum-up.
Character based Method:
It use the alligned sequences directly during tree inference.


For more details please watch the video below


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