BASICS
OF PHYLOGENETICS : Computational
Analysis of Distance and Character based methods
Distance based Method :
Transform the sequence data into pairwise distances and then use the matrix during tree building ignoring the characters.
- The distance based phylogenetic methods measure the distance from the dissimilarity observe between pairs of sequences, computed on the basis of sequence alignment.
- The main assumption of distance based methods is homologous and that tree branches can sum-up.
Character
based Method:
It use the alligned sequences directly during tree inference.
For more details please watch the video below
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